Description

Division of Genomic Medicine, Department of Medicine and Institute for Genomic Health | Icahn School of Medicine at Mount Sinai | New York City

Lead the integration of genomics into everyday medicine

The Icahn School of Medicine at Mount Sinai is seeking exceptional Assistant or Associate Professor tenure-track faculty candidates who are talented physicians and/or physician-scientists who will develop and implement genomic medicine programs within the Division of Genomic Medicine (DGM), Department of Medicine, and the Institute for Genomic Health (IGH).

Genomic medicine has arrived. AI-enabled analysis of millions of sequenced genomes linked to real-world clinical data is transforming how we predict, prevent, diagnose, and treat disease. Mount Sinai is one of the few places in the world where that transformation is happening inside a health system, at population scale, in one of the most diverse patient communities. The successful candidate will work under the leadership of Dr. Michael Murray, Chief of the Division of Genomic Medicine and Clinical Director of IGH, and Dr. Eimear Kenny, Founding Director of IGH.

Why Mount Sinai? The data, the clinic, the mission

Faculty enjoy full access to:

• The Genomic Screening Program and Genomic Health Clinic; pioneering programs returning actionable genomic results to patients and embedding genomic and polygenic risk information in routine clinical care Department of Medicine's Genomic Health Clinic
• The Mount Sinai Million Health Discoveries Program; launched in 2022 in partnership with the Regeneron Genetics Center, this landmark initiative is sequencing the genomes of one million racially and ethnically diverse Mount Sinai patients linked to their electronic health records, making it one of the largest and most diverse health-system-based sequencing efforts in the world.
• The BioMe Biobank; a pioneering EHR-linked germline DNA repository of more than 70,000 Mount Sinai patients, generating genomic discoveries since 2007.
• A state-of-the-art high-performance computing and AI ecosystem, including Mount Sinai’s Scientific Computing and Data Science resources, the Data Ark, and the AIRMS secure AI research platform.
• Major NIH-funded consortia and clinical partnerships, including eMERGE and its Polygenic Risk Score Program, CSER, ClinGen, TOPMed, GSP, PAGE, the Human Pangenome Reference Consortium, and the NIH All of Us Research Program. Clinically integrated across the Department of Medicine’s Divisions to promote Genomic Implementation across Adult Primary and Specialty Care.

You will be embedded in a fast-paced, highly collaborative team of clinician-scientists, data scientists, genetic counselors, health system researchers, and disease-area experts who share a single goal: translating large-scale genomic data into new paradigms for human health.

Current arenas of IGH and DGM research include mining deep genomic databases with machine learning and AI; basic and discovery science spanning population and statistical genetics, variant interpretation, structural variation, host genomics of infectious disease, and the genetics of complex and psychiatric traits; accelerating clinical genomic and polygenic risk prediction; running clinical trials that integrate genomic information and novel technology into routine care; and advancing health equity by building the resources, knowledge, and best practices needed to bring genomic medicine to diverse and underserved populations.

The Role

The successful candidate will be supported in developing new clinical collaborations for adult care and helping to build the rapidly expanding set of clinal collaborations for diagnostic testing and elective screening. We are building models for implementing genomic medicine programs and lead an independent research program leveraging cutting-edge health systems data. Research programs may span, but are not limited to:

Translating genomic information into novel therapies
Genomic and polygenic risk prediction for human diseases and preventive health
Genomic medicine implementation, including clinical trials, population screening, and implementation science in diverse populations
Clinical, basic, or translational research in human genetics and genomics

This will be a faculty appointment at a rank commensurate with experience, with a primary appointment in IGH and the Division of Genomic Medicine, Department of Medicine, consistently ranked among the top departments nationally for NIH funding. Tenure-track candidates are expected to obtain independent funding to grow and sustain their research program and will receive the institutional support and mentorship to do so.

Qualifications

MD or MD/PhD with expertise in clinical genetics and genomics.
Graduate Medical Training in Internal Medicine and/or Medical Genetics is a plus.
A track record of innovation and scholarship in the field, as evidenced by a strong publication record
A strong background in clinical, basic, or translational research in human genetics
Enthusiasm for team science in a collaborative, mission-driven environment
 

What We Offer

 Highly competitive recruitment packages, including generous start-up funding, protected research time, and dedicated computational resources
Strong institutional commitment to faculty mentorship, career development, and workforce diversity
Comprehensive benefits and relocation services
A rewarding work-life environment in the heart of Manhattan. Our offices are one block from Central Park.
 

How to Apply

Using this form, please attach your CV, research plan, and cover letter. Review of applications will begin immediately and continue until the positions are filled.

Strength Through Diversity

The Mount Sinai Health System believes that diversity and inclusion are drivers of excellence. We share a common devotion to delivering exceptional patient care — yet we’re as diverse as the city we call home: culturally, ethnically, in outlook and lifestyle. When you join us, you become part of Mount Sinai’s unrivaled record of achievement, education, and advancement as we revolutionize healthcare delivery together. We work hard to recruit and retain the best people and to create a welcoming, nurturing environment where you have the opportunity and support to develop professionally. We share the belief that all employees, regardless of job title or expertise, contribute to quality patient care.

Who We Are

More than 48,000 employees strong, the mission of the Mount Sinai Health System is to provide compassionate patient care with seamless coordination and to advance medicine through unrivaled education, research, and outreach in the many diverse communities we serve.

The Mount Sinai Health System combines the excellence of the Icahn School of Medicine at Mount Sinai with premier hospital campuses across the New York metropolitan area, including The Mount Sinai Hospital, Mount Sinai Queens, Mount Sinai Brooklyn, Mount Sinai West, Mount Sinai Morningside, Mount Sinai South Nassau, and New York Eye and Ear Infirmary of Mount Sinai.

The Mount Sinai Health System is an equal opportunity employer. We comply with applicable federal civil rights laws and do not discriminate, exclude, or treat people differently on the basis of race, color, national origin, age, religion, disability, sex, sexual orientation, gender identity, or gender expression.

EOE Minorities/Women/Disabled/Veterans

Requirements

MD or MD/PhD with expertise in clinical genetics and genomics.
Graduate Medical Training in Internal Medicine and/or Medical Genetics is a plus.
A track record of innovation and scholarship in the field, as evidenced by a strong publication record
A strong background in clinical, basic, or translational research in human genetics
Enthusiasm for team science in a collaborative, mission-driven environment